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Local StoreAmerica/New_York

CVS Pharmacy – W 42nd St Location (New York, NY)

Operating schedule, street address (500 W 42nd St), direct phone line, and department hours for the W 42nd St location in New York, New York.

Open NowCloses in 14 hr 55 min
9:04 AM EST
Wednesday’s Operating Schedule
8:00 AM – 11:59 PM (Front-store hours vary by store; pharmacy counter usually 8-9 AM to 6 PM, closed 1:30-2 PM)
Calculated for EST zone
Check Other US Timezones:

New York Metro Location Notice: Multiple Branches in Area

The New York metropolitan market is served by multiple CVS Pharmacy facilities. This directory page specifically displays hours, phone lines, and department amenities for the 500 W 42nd St (W 42nd St) branch.

Looking for a different neighborhood store?Find Nearest CVS Pharmacy on Official Locator
Confirmed On-Site Departments & Services at this Branch:
Pharmacy CounterMinuteClinicPhoto LabPassport PhotosCurbside Pickup
Physical Address
CVS Pharmacy

500 W 42nd St
New York, NY 10001

Direct Phone Line
(212) 244-4285

Connect directly with store customer service, prescription status, or store inventory confirmation during active hours.

Data Details

Data Source: Based on CVS Health corporate schedule systems.

Timezone: America/New_York

New York Branch Operating Hours

America/New_York
Sunday
8:00 AM – 11:59 PM
Front-store hours vary: some stores 24 hours, many 8 AM to midnight. Pharmacy counter usually 10 AM-5 PM
Monday
8:00 AM – 11:59 PM
Front-store hours vary by store; pharmacy counter usually 8-9 AM to 6 PM, closed 1:30-2 PM
Tuesday
8:00 AM – 11:59 PM
Front-store hours vary by store; pharmacy counter usually 8-9 AM to 6 PM, closed 1:30-2 PM
Wednesday
8:00 AM – 11:59 PM
Front-store hours vary by store; pharmacy counter usually 8-9 AM to 6 PM, closed 1:30-2 PM
Thursday
8:00 AM – 11:59 PM
Front-store hours vary by store; pharmacy counter usually 8-9 AM to 6 PM, closed 1:30-2 PM
Friday
8:00 AM – 11:59 PM
Front-store hours vary by store; pharmacy counter usually 8-9 AM to 6 PM, closed 1:30-2 PM
Saturday
8:00 AM – 11:59 PM
Front-store hours vary by store; pharmacy counter usually 9-10 AM to 6 PM

Shopping Guide & Location Overview: CVS Pharmacy in New York, NY

Serving the greater New York metropolitan area, this confirmed CVS Pharmacy branch at 500 W 42nd St provides convenient access for residents and commuters across New York. Operating within the America/New_York time zone, the store adheres to standard regional retail cycles, maintaining a predictable weekly schedule designed to serve morning errands, lunchtime shoppers, and after-work visits.

Local Store Features & Logistics:Located at 10th Ave & 42nd St in Manhattan, this high-density urban CVS operates 24 hours daily with walk-in prescription and photo processing counters.

When planning your visit, note that customer traffic peaks on Saturday afternoons and weekday evenings between 4:30 PM and 7:00 PM. Shoppers seeking rapid checkout times or specialized counter consultations (such as returns, bulk inquiries, or specialized department assistance) are encouraged to visit during the quietest operational window between 10:00 AM and 1:00 PM on Tuesday through Thursday.

Parking accommodations at this location feature dedicated customer parking bays, accessible stalls adjacent to main entrances, and convenient turnaround access for app-based pickup services. If you require assistance regarding item availability, specialized holiday schedules, or wheelchair accessibility, contacting the store front desk at (212) 244-4285 prior to departure will ensure a seamless shopping experience.